While researching the study methods for Part 1 (You can read it here!)
I stumbled upon a study method that I had not been familiar with.
But apparently, it has a very big impact on our education, careers as doctors and patients.
( Or skip the reading and get to studying directly at MedlyCase! )
So today, we are going to talk about something deeper and way more important than actually memorising drug names.
It is our ability to “think about thinking“ as doctors, so-called metacognition.
If there is one thing that you need to take away from this email, it is that this is NOT important for you, but for your patients, and it is the foundation of being a lifelong learner.
“Metacognition has the potential to reduce diagnostic errors and improve patient safety “
Royce CS et al, Teaching Critical Thinking: A Case for Instruction in Cognitive Biases to Reduce Diagnostic Errors and Improve Patient Safety.

This was difficult for me to understand, so bear with me while I try to make sense of it all.
Let’s dive deep into metacognition!
Please let me know if this content is useful, fun, or if you have any suggestions by sending a quick message to [email protected] or @medlycase on Instagram.
What is even Metacognition?
Metacognition is thinking about thinking.

Fun motivation to keep on reading
It is like the voice inside our head saying, “Do I really understand this, or do I think that I do?“
It is knowing how you think, and by knowing how you think, detecting possible errors and possible shortcuts for better retention and learning.
Components of Metacognition
Metacognition has two core components - knowledge and regulation based on that knowledge:
Metacognitive knowledge — what you know about how you learn (e.g., "I retain information better by teaching it to others")
Metacognitive regulation — actively controlling your learning based on that knowledge (e.g., planning, monitoring comprehension, adjusting strategy when something isn't working)
How does this apply to medical school?
If we know how we retain and learn information the best (flashcards, teaching, lectures).
Then we can use this information to guide our studying - plan our studying, monitor our progress, and adjust along the way.

Let me know if this makes sense.
Let me give an example from myself.
Knowledge - I learn best by doing flashcards (HOW) and applying the knowledge (e.g., cases in medicine) (HOW).
Regulation - So I use a flashcard app + read cases (PLAN).
But once I realise I don’t understand a certain concept despite the information on the flashcard, I opt for another resource or ask my teachers (ADJUST).
I actively monitor myself by doing MCQ and MedlyCase Exam Mode (MONITOR)
I am also aware of my pitfalls (I have many!!!). I have a hard time understanding the cascade of events (like in Endocrinology), but I understand more concrete surgical strategies easily. So I naturally tend to spend more time studying endocrinology rather than general surgery.
If you find this useful and interesting, why not try some of our cases in MedlyCase and challenge yourself? Here is the link!

Metacognition remains as a skill that can be used throughout our careers as doctors
How does this apply to being a doctor?
Metacognition is very useful while studying, BUT it is critical when we practice medicine, especially for patient safety.
Because it allows us to reduce the mistakes that can happen due to faulty knowledge, biases, and overconfidence.
Metacognition in clinical practice again consists of awareness of our knowledge and regulating our thinking.
Here is an example in action from my own practice.
I do have the pediatric antibiotic and analgesic doses per weight memorized (Awareness), but I know that when rushed in the emergency room, I tend to make mathematical mistakes (Pitfall), so I always double-check the doses with a verified dose calculator (Adjust).
If I had not been aware of my pitfall, I might have mistakenly given the wrong dose.
In the clinical environment, metacognition directly translates to diagnostic humility. It's the habit of asking:
"Am I anchoring on my first impression?"
"What am I missing? What doesn't fit?"
"Should I reconsider this diagnosis?"
This is essentially metacognition applied in real time at the bedside, and it's a core component of avoiding cognitive errors, and more on them below
If you want to practice improving your metacognition in a safe environment, why don’t you just try a case in MedlyCase, and while you are doing the case, ask yourself questions such as “Is this the final diagnosis? “Am I missing out on anything“ “Where could I be making a mistake?
If you are unsure where to start, feel free to email me at [email protected], and we can practice together!
Using Metacognition while Studying in Medical School
So now that we have covered the importance of metacognition, let’s see how we can implement it into your studying regime.
We will divide studying into two parts, depending on the knowledge: theoretical knowledge and clinical/practical knowledge

Summary: If you want to reuse this image, you have to do one case in MedlyCase!
1. How to study theoretical knowledge in Med School
This section is all about the theoretical parts — pharmacology, pathophysiology, anatomy, and biochemistry.
You need to personalise your studying routine.
For your own thoughts.
The core habit is active self-monitoring while you study. This means continuously asking yourself: "Do I actually understand this, or does it just look familiar?"
Here are some actionable steps:
Self-test constantly.
We covered this in Part 1. Active Recall and Spaced Repetition!
Identify your knowledge gaps.
After self-testing, don't just note what you got wrong - categorize why.
Was it a gap in foundational knowledge?
A reasoning error?
A concept you never properly understood in the first place?
This distinction matters because each requires a different response.
Adjust your strategy based on what the evidence tells you.
If you've been using one method and you are not getting the desired results, switch!
If flashcards do not work, but watching online lectures does.
Then double down on the online lectures
Metacognition means being willing to adapt and change.
Reflect on what worked after each study block.
A simple 2-minute reflection
"What did I actually learn today? What is still unclear? What will I do differently tomorrow?"
This creates a feedback loop that compounds over time.
The evidence also supports personalizing your approach based on your own metacognitive profile.
This is exactly what I do myself —- spending more time on endocrinology because I know cascades are my weak point, using Anki because I know active recall works for me, using MedlyCase to monitor whether my knowledge actually transfers to application.
2. How to study clinical/practical knowledge in Med School
In my opinion, this is the section where things get very important. I cannot stress out how important this is when you are facing a REAL patient in a real clinical setting.
It is not only studying, but also the foundation of being a good doctor.
Here is how to do it according to the latest science.
1. Deliberate Reflection — Pause and Question Yourself
After working through a clinical case or seeing a patient, don't just move on.
Pause and ask yourself: "What was my initial impression? Was I right? What could I have missed? What evidence pushed me toward that conclusion?"
This is the strategy with the strongest evidence behind it.
Research shows that guided reflection - systematically reviewing your reasoning, considering alternatives, and challenging your assumptions - directly improves diagnostic accuracy and reduces cognitive errors.
In practice, this could look like: after finishing a case on MedlyCase or seeing a patient in the clinic, spending 2–3 minutes thinking or writing what you got wrong, but why your reasoning went in the direction it did, and what you can do to improve.
2. Metacognitive Checklists -Structure Your Self-Monitoring
When working through clinical cases, structured checklists help prevent premature closure, which is the bias of settling on an answer too early.
One example from the literature is the TWED mnemonic, which prompts you to systematically review your reasoning during history-taking and examination.
T = Threat ("Is there any life or limb threat that I need to rule out in this patient?")
W = What if I am wrong? What else? ("What if my diagnosis is incorrect? What other possibilities should I consider?")
E = Evidence ("Do I have sufficient evidence to support or exclude this diagnosis?")
D = Dispositional influence ("Are there any personal or contextual factors influencing my decision?").
I did not know the literature behind this until researching this article. But I use this a lot in the Emergency Room in my practice, and I am glad the habit was formed by my university.
3. Self-Explanation and Concept Mapping — Build Deeper Understanding
When you encounter a concept you're struggling with, try explaining it out loud as if teaching someone else.
This forces you to identify exactly where your understanding breaks down.
Concept mapping (visually connecting related ideas) is useful for topics like endocrinology, where understanding cascades of events is the challenge.
The End!
What a long essay!
Thank you for reading, and I hope you found it interesting and useful. If you would like to train your metacognition in a safe environment, head to Medlycase.com or drop me an email at [email protected], and we can do it together.
References
Deliberate Reflection and Clinical Reasoning: Founding Ideas and Empirical Findings. Mamede S, Schmidt HG. Medical Education. 2023;57(1):76-85. doi:10.1111/medu.14863.
Dual-Process Cognitive Interventions to Enhance Diagnostic Reasoning: A Systematic Review. Lambe KA, O'Reilly G, Kelly BD, Curristan S. BMJ Quality & Safety. 2016;25(10):808-20. doi:10.1136/bmjqs-2015-004417.
Teaching Metacognition in Clinical Decision-Making Using a Novel Mnemonic Checklist: An Exploratory Study. Chew KS, Durning SJ, van Merriënboer JJ. Singapore Medical Journal. 2016;57(12):694-700. doi:10.11622/smedj.2016015.
A Metacognitive Confidence Calibration (MCC) Tool to Help Medical Students Scaffold Diagnostic Reasoning in Decision-Making During High-Fidelity Patient Simulations. Garbayo LS, Harris DM, Fiore SM, Robinson M, Kibble JD. Advances in Physiology Education. 2023;47(1):71-81. doi:10.1152/advan.00156.2021.
The Influence of Medical Students' Self-Explanations on Diagnostic Performance. Chamberland M, St-Onge C, Setrakian J, et al. Medical Education. 2011;45(7):688-95. doi:10.1111/j.1365-2923.2011.03933.x.
The Effectiveness of Concept Mapping as a Tool for Developing Critical Thinking in Undergraduate Medical Education - A BEME Systematic Review: BEME Guide No. 81. Fonseca M, Marvão P, Oliveira B, et al. Medical Teacher. 2024;46(9):1120-1133. doi:10.1080/0142159X.2023.2281248.
Learning Techniques That Medical Students Use for Long-Term Retention: A cross-Sectional Analysis. Urrizola A, Santiago R, Arbea L. Medical Teacher. 2023;45(4):412-418. doi:10.1080/0142159X.2022.2137016.
Incorporating Structured Metacognitive Training Into an Undergraduate Anatomy Classroom. Ruth AA, Dzara K. Anatomical Sciences Education. 2025;18(1):87-96. doi:10.1002/ase.2537.
Strategies for Improving Learner Metacognition in Health Professional Education. Medina MS, Castleberry AN, Persky AM. American Journal of Pharmaceutical Education. 2017;81(4):78. doi:10.5688/ajpe81478.
Promoting Metacognition in an Allied Health Anatomy Course. Cale AS, Hoffman LA, McNulty MA. Anatomical Sciences Education. 2023 May-Jun;16(3):473-485. doi:10.1002/ase.2218.
